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Line integrals of vector fields
A vector field can do work along a path when its component in the direction of motion is accumulated along that path.
Let a curve $C$ be parametrized by
$$\mathbf r(t),\qquad a\le t\le b,$$
and let $\mathbf F$ be a vector field. The line integral of $\mathbf F$ along $C$ is
$$\int_C\mathbf F\cdot d\mathbf r
\int_a^b\mathbf F(\mathbf r(t))\cdot\mathbf r'(t),dt.$$
Work
If $\mathbf F$ is a force field and $C$ is the path of an object, then
$$W=\int_C\mathbf F\cdot d\mathbf r$$
is the work done by the force along the path.
Only the component of the field tangent to the motion contributes to the integral.
Orientation matters
Reversing the path changes $d\mathbf r$ to its negative, so
$$\int_{-C}\mathbf F\cdot d\mathbf r =-\int_C\mathbf F\cdot d\mathbf r.$$
This differs from a scalar line integral with respect to $ds$, which does not depend on orientation.
Circulation
When $C$ is a closed curve, the notation
$$\oint_C\mathbf F\cdot d\mathbf r$$
is often used. It measures the circulation of the field around the loop.
Line integrals of vector fields connect a field distributed through space with its accumulated tangential effect along a chosen oriented path.