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Lines and slope in the coordinate plane
A straight line has a constant rate of change: whenever $x$ changes by the same amount, $y$ changes by a proportional amount. That rate is the slope.
For two points $(x_1,y_1)$ and $(x_2,y_2)$ on a nonvertical line,
$$m=\frac{y_2-y_1}{x_2-x_1}=\frac{\Delta y}{\Delta x}.$$
Interpreting slope
A positive slope rises from left to right, a negative slope falls, and zero slope gives a horizontal line. A vertical line has $\Delta x=0$, so its slope is undefined.
For example, the line through $(1,2)$ and $(4,8)$ has
$$m=\frac{8-2}{4-1}=2.$$
This means that $y$ increases by $2$ for each increase of $1$ in $x$.
Equations of lines
A line with slope $m$ and vertical intercept $b$ can be written
$$y=mx+b.$$
If a point $(x_1,y_1)$ and the slope are known, the point-slope form is
$$y-y_1=m(x-x_1).$$
Both equations describe the same geometric object in different ways.
Parallel and perpendicular lines
Distinct nonvertical parallel lines have the same slope. Perpendicular nonvertical lines have slopes whose product is $-1$ when both slopes are defined, so their slopes are negative reciprocals.